locus coeruleus

A pons region {locus coeruleus}| can receive feedback from sense cortex and send to spinal cord, hypothalamus, tractus solitarius nucleus, sensory cerebral cortex, and cerebellum Purkinje cells [Foote and Morrison, 1987] [Foote et al., 1980] [Hobson, 1999]. Locus coeruleus contains few thousand neurons and is largest noradrenaline nucleus.

transmitters

Locus-coeruleus neurons contain neuropeptide Y (NPY) and galanin peptide transmitters.

functions

Locus coeruleus suppresses tonic vegetative regions. It regulates attention, pleasure, energy, motivation, and arousal. It causes deep sleep. REM sleep, cataplexy, grooming, and feeding depress it. Interruptions and multimodal somatosensory stimuli, including pain, excite it. Locus-coeruleus electrical stimulation causes fear and anxiety.

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Date Modified: 2022.0224