human immunodeficiency disease

HIV-1 and HIV-2 retroviruses {human immunodeficiency virus}| [1983] can cause disease {acquired immunodeficiency syndrome} (AIDS).

virus

In all retroviruses, env gene is for coat proteins, gag gene is for core proteins, and pol gene is for reverse transcriptase and other viral enzymes.

In HIV, nef gene is for high infection. rev gene is for movement of RNA to cytoplasm. tat gene is for HIV-gene expression. vif gene is for higher infection. vpr gene is for transcription activation. vpu gene is for assembly and budding.

drug

Dideoxynucleoside anti-HIV drug {azidothymidine} (AZT) substitutes for thymidine in DNA and so prevents making DNA sequences in high-replication cells, such as retrovirus-containing cells and bone-marrow blood-precursor cells. Protease inhibitors block HIV protease, which cleaves gag protein and pol protein. Adjuvants stimulate immune system, which can help anti-HIV drugs.

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4-Medicine-Disease-Kinds-Organism-Virus

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Date Modified: 2022.0224