interferon

Small proteins {interferon}| can bind to plasma membranes and can protect against viruses that degrade mRNA and block protein-synthesis initiation. After viral-gene expression starts, interferon can stop all viral-gene expression {interferon response}. In humans, viruses that make long double-stranded RNAs trigger PKR enzyme production, which stops mRNA translation to protein. RNAse L breaks down mRNA. Interferon cytokine secreted by virus-infected cells enhances both these responses.

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