Chemicals can inhibit drugs {drug inhibition}. Inhibitor has binding constant.
Inhibitor can bind to non-active site {allosteric non-competitive inhibition}.
Drugs {entry inhibitor} can prevent viruses from entering cells.
Drugs {integrase inhibitor} can prevent virus DNA from inserting into host DNA.
Drugs {maturation inhibitor} can block gag-protein protease receptor, so gag protein is not split, and HIV virus coat is not made. PA-457 comes from betulinic acid from Taiwan herb, plane trees, and birch trees.
Metabolized compounds can bind to enzymes {mechanism-based inhibition}.
Drugs {protease inhibitor} can inhibit protease enzymes.
5-Chemistry-Biochemistry-Drug-Metabolism
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Date Modified: 2022.0225