Chromatography {liquid-solid chromatography} {adsorption chromatography} can separate non-polar molecules with different steric or spatial configurations. Adsorption chromatography can separate large amounts. Solid phase is silica, calcium carbonate, charcoal, or alumina, which all adsorb liquid solvents well. Eluant solvent flows past solid, carrying molecules to analyze. Bigger molecules and more polar molecules adsorb better and move slower. Second eluant can elute high-polarity molecules that stay in solid.
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Date Modified: 2022.0224