pyramidal cell

Excitatory neurons {pyramidal cell}| can connect one cortical area to another and fire in bursts. Pyramidal cells are both superficial and deep [Elston, 2000] [Elston and Rosa, 1997] [Elston and Rosa, 1998] [Elston et al., 1999].

functions

Pyramidal cells detect fast moving stimuli, such as moving edge at one orientation.

output

Cerebral cortex layer-5 pyramidal cells send to thalamic nuclei, mainly to lateral geniculate nucleus and inferior, lateral, and medial pulvinar nuclei. Half of layer-6 pyramidal cells send to lateral geniculate nucleus, and others send to claustrum, hippocampal system, and anterior cingulate sulcus motor-system higher planning levels. Pyramidal cells with short dendrites, not reaching into layer 1, send to other cerebral cortex regions. Excitatory extrinsic axons come from pyramidal cells. Pyramidal cells also send to local neurons using axon collaterals.

Pyramidal cells inhibit stellate cells. Pyramidal-cell to stellate-cell ratio is two to one.

processing

Pyramidal cells have high spontaneous activity and large receptive fields. Sustained intracellular current causes high-frequency action potentials {regular spiking cell}, which decrease within 50 to 100 milliseconds.

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