Chemicals {retrograde messenger} can diffuse back from postsynaptic to presynaptic membrane. For example, upon protein-kinase activation, nitric oxide synthase makes nitric oxide from l-arginine. Nitric oxide diffuses back from postsynaptic to presynaptic membrane and causes increase in vesicle release, if membrane is still active.
Biological Sciences>Zoology>Organ>Nerve>Neural Chemical>Modulator
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Date Modified: 2022.0224