medial temporal lobe

Temporal regions {middle temporal lobe} {medial temporal lobe} (MT) {mediotemporal cortex} {V5 brain area} {area V5} can encode motion perception and respond to movement and movement direction but not to wavelength. MT can detect movement direction, from visual texture [Albright, 1993] [Allman and Kaas, 1971] [Andersen, 1997] [Britten et al., 1992] [Britten et al., 1996] [Cook and Maunsell, 2002] [Ditterich et al., 2003] [Goebel et al., 1998] [Goldstein and Gelb, 1918] [Heeger et al., 1999] [Hess et al., 1989] [Heywood and Zihl, 1999] [Huk et al., 2001] [Humphreys, 1999] [Mather et al., 1998] [Parker and Newsome, 1998] [Salzman and Newsome, 1994] [Salzman et al., 1992] [Schall, 2001] [Shadlen et al., 1996] [Tootell and Taylor, 1995] [Tootell et al., 1995] [Tolias et al., 2001] [Williams et al., 2003] [Zeki, 1974] [Zeki, 1991] [Zihl et al., 1983].

MT neurons can code for depth [Bradley et al., 1998] [Cumming and DeAngelis, 2001] [DeAngelis et al., 1998] [DeAngelis and Newsome, 1999] [Grunewald et al., 2002] [Maunsell and Van Essen, 1983].

memory

Medial temporal lobe stores long-term declarative explicit memories. MT also participates in recognition memory.

attention

Attention affects medial temporal lobe [McAdams and Maunsell, 2000] [Saenz et al., 2002] [Treue and Martinez-Trujillo, 1999].

anatomy

MT includes amygdala, entorhinal cortex, hippocampus, parahippocampal gyrus, perirhinal cortex, and Brodmann areas 28, 35, 36, and 37.

input

MT receives from V1 and superior colliculus. Parahippocampal and perirhinal cortex both receive from somatic, auditory, and visual sensory cortex. Entorhinal cortex receives from parahippocampal and perirhinal cortex. Hippocampus DG region receives most from entorhinal cortex and some from parahippocampal and perirhinal cortex, not from neocortex. Hippocampus CA3 receives from DG. Hippocampus CA1 receives from CA3. Subiculum, in hippocampal formation, receives from CA1.

output

MT sends to superior colliculus, posterior parietal lobe, lateral intraparietal lobe, ventral intraparietal lobe, medial superior temporal lobe, and frontal lobe. MT connects through pons nuclei to cerebellum to control body and eye movements. Subiculum sends to rhinal cortex, which sends to sensory cortex.

damage

MT damage over wide area impairs factual knowledge retrieval but not information about categories or object features. Damage impairs smell but nothing else. Damage does not affect attention. Damage also affects emotions. Damage causes retrograde amnesia and affects all senses.

evolution

All primates have visual area 5.

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Biological Sciences>Zoology>Organ>Nerve>Brain>Cerebrum>Temporal Lobe

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Date Modified: 2022.0224