Barbiturates and other drugs {sedative} can lower brain activity {sedation, drugs} and make people sleepy. Drugs {GABAergic drug} can bind to gamma-aminobutyric acid (GABA) receptors and increase GABA effect. Hypnotic drugs and weak tranquilizers act similarly. Going to sleep also requires GABA receptor binding that increases effect of GABA. Barbiturates are addictive and eliminate Stage-IV NREM sleep and REM sleep. Benzodiazepines, such as Valium, are addictive, reduce anxiety, and eliminate Stage-IV NREM sleep. Sedatives {gamma-amino-hydroxybutyrate} (GHB) can be for mood {euphoriogenic drug} and anxiety {anxiolytic drug, sedative}. Zolpidem (Ambien) is much less addictive.
Nucleotides {adenosine, sleep} can cause sleep.
Interleukins {interleukin-1} can induce non-REM sleep.
Outline of Knowledge Database Home Page
Description of Outline of Knowledge Database
Date Modified: 2022.0225