Chromosome-4-tip autosomal dominant gene can cause Huntington's chorea and related diseases {polyglutamine disease, protein}. Gene has middle cytosine-adenine-guanine repeats {CAG repeat, polyglutamine} that repeat too many times, making too many glutamine amino acids, and this causes proteins to clump. Cytosine-anything-guanine regions {CxG region, polyglutamine} have many DNA hairpins, and copies often have even longer CxG repeats. Huntington's disease and polyglutamine diseases first have many protofibrils and then plaques.
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4-Medicine-Disease-Kinds-Protein
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Date Modified: 2022.0224