amyloid plaque

Protein-polysaccharide fragments {A-beta protein} can link hydrophobic ends to form extracellular plaques {amyloid plaque}|, create free radicals, or attract microglia. Apolipoprotein E (APOE) helps A-beta protein form plaques. APOE-4 slows A-beta protein removal. Perhaps, A-beta protein disrupts calcium regulation.

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