4-Genetics-Virus

virus genetics

SV40 monkey virus and mouse polyoma virus {virus, genetics}| have circular DNA with 10 genes.

replication phases

In replication early phase, cells make T antigen. In late phase, viral DNA replicates, and cells make coat proteins.

complementary DNA

RNA tumor viruses make complementary DNA by reverse transcriptase. Complementary DNA makes double-stranded DNA that enters host genome and makes RNA virus.

RNA

Tobacco mosaic virus, influenza virus, poliovirus, RNA phages, and other RNA viruses have single-stranded RNA, which replicates using RNA replicase. Single-stranded RNA also acts as mRNA to make viral proteins.

coat protein

Coat proteins surround virus and phage nucleic acid. M13-phage gene III codes coat protein. Genes cloned into Gene III appear on phage surfaces {phage display}. Tobacco mosaic viruses and other mild plant viruses have coat proteins that protect against worse viruses.

T antigen

In replication early phase, cells make viral proteins {T antigen} {tumor protein} for virus DNA replication.

TT virus

Circinoviridae single-stranded circular DNA {TT virus} (TTV) is similar to Circoviridae DNA.

virus-like particle

Virus structural proteins can arrange to make particles {virus-like particle} (VLP) with virus shapes and sizes.

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Date Modified: 2022.0225