cytochrome b gene

Nuclear genes {cytochrome b gene} can make mitochondrial respiratory-chain proteins.

cybS

Nuclear genes {cybS gene} {SDHD gene, cytochrome} can make small cytochrome-b subunits. cybS protein is in mitochondria protein complexes {mitochondrial complex II} {succinate-ubiquinone oxidoreductase}, which are in electron transport chains.

Perhaps, cybS genes are tumor suppressor genes, because they are typically not in bladder, breast, cervix, stomach, lung, and ovary cancers or in melanomas. Perhaps, cybS protein is in carotid-body oxygen-sensing system. Without cybS protein, chronic hypoxic stimulation causes cell proliferation. Solid tumors are typically hypoxic compared to normal tissues.

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4-Genetics-Gene-Respiratory Chain

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Date Modified: 2022.0224