gap gene

After first cell divisions, genes {gap gene} {hunchback gene} {hunchback-maternal gene} {knirps gene} {Kruppel gene} can code zinc-finger transcription factors that make bands along embryo and body regions by working with maternal-effect genes and by repressing each other. Gap genes also regulate genes expressed later. Transcription-factor binding sites are high-affinity or low-affinity, so transcription-factor concentration affects which genes transcribe and how much, leading to gradients and bands. In small regions, same chemicals cause different effects.

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