Factors {hepatic nuclear factor-1-alpha} {HNF-1-alpha} can have dimerization domains, which have mini-zipper four-helix-bundle (4HBs) superfamilies. Low transcription factor affects glucose-metabolism regulation, because dimers bind anti-parallel to coactivator protein {DCoH protein} to start insulin secretion in response to glucose.
Biological Sciences>Genetics>DNA Regulation>Protein
4-Genetics-DNA Regulation-Protein
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Date Modified: 2022.0224