Tissue damage, inflammation, and high-intensity stimuli release chemicals that excite nociceptors. Pain detects and measures relative concentrations of pain-causing chemicals released by body inelastic strains or tissue damage. People can distinguish strength and type of pain.
High pressure, high temperature, harsh sound, intense light, and sharp smells and tastes cause neuron changes {pain, causes}. Inflammation or acute-pain aftereffects can cause pain.
Pain involves too much small-nerve-fiber activity, uninhibited by large neurons. Blows to body release histamines, bradykinin, and prostaglandins, which excite neurons. Gut distension causes pain, but gut squeezing, cutting, and burning do not. Infection can amplify pain. Tissue damage can amplify pain. Damaged tissue activates immune cells, which release molecules that excite nerves and glia. Arginine vasopressin, encephalin, endorphin, and substance P can affect pain.
Randomly placed brainstem electrodes produce pain 5% of time. Direct cerebral-cortex stimulation can cause other sense qualities but never causes pain. Cortex stimulation does not decrease pain.
Consciousness>Consciousness>Sense>Pain>Physiology
1-Consciousness-Sense-Pain-Physiology
Outline of Knowledge Database Home Page
Description of Outline of Knowledge Database
Date Modified: 2022.0224